Ladies and Gentlemen,
On behalf of the Board of Directors of Orphinic Scientific S.A., I hereby notify you of the convening of the Extraordinary General Meeting of Orphinic Scientific S.A. on November 4, 2025 at 10:00 a.m., which will be held at the registered office of the Company, in the Notary Office of Rafał Brandt, Joanna Okońska, Sebastian Chaber Notaries s.c., 46A Mokotowska Street, loc.27.
Please find below the said Notice and Request from the Board of Directors of Orphinic Scientific S.A.